Let's start the curation of Human proteins

Below we printed the 50 complexes that are the most likely to be errors according to our "error-score".

The "error-score" is a two digits number ranging between 0 and 19. (i) The first number if "1", indicates lack of symmetry, and (ii) the second number indicates the % sequence identity at which a homolog with a different symmetry has been found.

For example, an error score of 19 means: (i) the structure has no symmetry, and (ii) there is a homolog with 100% seq. id. that is itself symmetric.

Error Score Code Gene ID Pic Sym Nsub H Org Fun
19 1l6l_6 ENSP00000356969 NA NS 2 H Structures of Apolipoprotein A-II and a Lipid Surrogate Complex Provide Insights into Apolipoprotein-Lipid Interactions LIPID TRANSPORT
19 1l6l_13 ENSP00000356969 NA NS 2 H Structures of Apolipoprotein A-II and a Lipid Surrogate Complex Provide Insights into Apolipoprotein-Lipid Interactions LIPID TRANSPORT
19 1l6l_5 ENSP00000356969 NA NS 2 H Structures of Apolipoprotein A-II and a Lipid Surrogate Complex Provide Insights into Apolipoprotein-Lipid Interactions LIPID TRANSPORT
19 2c0m_1 ENSP00000266564 NA NS 2 H APO FORM OF THE TPR DOMAIN OF THE PEX5P RECEPTOR TRANSPORT PROTEIN
19 1l6l_12 ENSP00000356969 NA NS 2 H Structures of Apolipoprotein A-II and a Lipid Surrogate Complex Provide Insights into Apolipoprotein-Lipid Interactions LIPID TRANSPORT
19 1t3n ENSP00000217800 NA C2 4 H Structure of the catalytic core of DNA polymerase Iota in complex with DNA and dTTP replication/DNA
19 1y1a ENSP00000333873 NA C2 4 H CRYSTAL STRUCTURE OF CALCIUM AND INTEGRIN BINDING PROTEIN METAL BINDING PROTEIN
19 1l6l_4 ENSP00000356969 NA NS 2 H Structures of Apolipoprotein A-II and a Lipid Surrogate Complex Provide Insights into Apolipoprotein-Lipid Interactions LIPID TRANSPORT
19 1l6l_11 ENSP00000356969 NA NS 2 H Structures of Apolipoprotein A-II and a Lipid Surrogate Complex Provide Insights into Apolipoprotein-Lipid Interactions LIPID TRANSPORT
19 1l6l_3 ENSP00000356969 NA NS 2 H Structures of Apolipoprotein A-II and a Lipid Surrogate Complex Provide Insights into Apolipoprotein-Lipid Interactions LIPID TRANSPORT
19 1l6l_9 ENSP00000356969 NA NS 2 H Structures of Apolipoprotein A-II and a Lipid Surrogate Complex Provide Insights into Apolipoprotein-Lipid Interactions LIPID TRANSPORT
19 1l6l_10 ENSP00000356969 NA NS 2 H Structures of Apolipoprotein A-II and a Lipid Surrogate Complex Provide Insights into Apolipoprotein-Lipid Interactions LIPID TRANSPORT
19 2ayn ENSP00000261601 NA NS 3 H Structure of USP14, a proteasome-associated deubiquitinating enzyme HYDROLASE
19 1l6l_2 ENSP00000356969 NA NS 2 H Structures of Apolipoprotein A-II and a Lipid Surrogate Complex Provide Insights into Apolipoprotein-Lipid Interactions LIPID TRANSPORT
19 1ykb ENSP00000329384 NA NS 6 H Crystal Structure of Insect Cell Expressed IL-22 CYTOKINE
19 1l6l_8 ENSP00000356969 NA NS 2 H Structures of Apolipoprotein A-II and a Lipid Surrogate Complex Provide Insights into Apolipoprotein-Lipid Interactions LIPID TRANSPORT
19 1l6l_1 ENSP00000356969 NA NS 2 H Structures of Apolipoprotein A-II and a Lipid Surrogate Complex Provide Insights into Apolipoprotein-Lipid Interactions LIPID TRANSPORT
19 1ogs ENSP00000357357 NA NS 2 H HUMAN ACID-BETA-GLUCOSIDASE HYDROLASE
19 1l6l_14 ENSP00000356969 NA NS 2 H Structures of Apolipoprotein A-II and a Lipid Surrogate Complex Provide Insights into Apolipoprotein-Lipid Interactions LIPID TRANSPORT
18 1o6u ENSP00000316203 NA NS 3 H THE CRYSTAL STRUCTURE OF HUMAN SUPERNATANT PROTEIN FACTOR TRANSFERASE
18 2h61 ENSP00000291700 NA D2 8 H X-ray structure of human Ca2+-loaded S100B METAL BINDING PROTEIN, SIGNALING PROTEIN
18 1key ENSP00000374332 NA C2 4 H Crystal Structure of Mouse Testis/Brain RNA-binding Protein (TB-RBP) RNA BINDING PROTEIN
12 2fv7 ENSP00000306817 NA NS 2 H Crystal structure of human ribokinase TRANSFERASE
11 1bwn ENSP00000361993 NA C2 4 H PH DOMAIN AND BTK MOTIF FROM BRUTON'S TYROSINE KINASE MUTANT E41K IN COMPLEX WITH INS(1,3,4,5)P4 TRANSFERASE
11 1b55 ENSP00000361993 NA C2 4 H PH DOMAIN FROM BRUTON'S TYROSINE KINASE IN COMPLEX WITH INOSITOL 1,3,4,5-TETRAKISPHOSPHATE TRANSFERASE
11 1cvi ENSP00000337471 NA C2 4 H CRYSTAL STRUCTURE OF HUMAN PROSTATIC ACID PHOSPHATASE HYDROLASE
9 1xap ENSP00000332296 NA NPS 1 H Structure of the ligand binding domain of the Retinoic Acid Receptor beta TRANSCRIPTION
9 1n7i_2 ENSP00000269582 NA NPS 1 H The structure of Phenylethanolamine N-methyltransferase in complex with S-adenosylhomocysteine and the inhibitor LY134046 TRANSFERASE
9 1nfk ENSP00000378310 NA C2 2 H STRUCTURE OF THE NUCLEAR FACTOR KAPPA-B (NF-KB) P50 HOMODIMER TRANSCRIPTION/DNA
9 1ozw_1 ENSP00000216117 NA NPS 1 H Crystal Structures of the Ferric, Ferrous and Ferrous-NO Forms of the Asp140Ala Mutant of Human Heme Oxygenase-1: Catalytic Implications OXIDOREDUCTASE
9 2nt1_4 ENSP00000357357 NA NPS 1 H Structure of acid-beta-glucosidase at neutral pH Hydrolase
9 2ooz ENSP00000215754 NA C3 3 H Macrophage Migration Inhibitory Factor (MIF) Complexed with OXIM6 (an OXIM Derivative Not Containing a Ring in its R-group) ISOMERASE
9 2huw_2 ENSP00000376347 NA NPS 1 H X-ray crystal structure of the Grb2 SH2 domain complexed to a constrained and cyclopropane-derived ligand HORMONE/GROWTH FACTOR
9 1s13_2 ENSP00000216117 NA NPS 1 H Human Heme Oxygenase Oxidatition of alpha- and gamma-meso-Phenylhemes oxidoreductase
9 1twn ENSP00000216117 NA C2 2 H Crystal structures of ferrous and ferrous-NO forms of verdoheme in a complex with human heme oxygenase-1: catalytic implications for heme cleavage OXIDOREDUCTASE
9 1jxq_2 ENSP00000330237 NA C2 2 H Structure of cleaved, CARD domain deleted Caspase-9 HYDROLASE
9 1s8c_3 ENSP00000216117 NA NPS 1 H Crystal structure of human heme oxygenase in a complex with biliverdine OXIDOREDUCTASE
9 1r2d ENSP00000302564 NA NPS 1 H Structure of Human Bcl-XL at 1.95 Angstroms APOPTOSIS
9 2jbj ENSP00000256999 NA NPS 1 H MEMBRANE-BOUND GLUTAMATE CARBOXYPEPTIDASE II (GCPII) IN COMPLEX WITH 2-PMPA (2-PHOSPHONOMETHYL-PENTANEDIOIC ACID) HYDROLASE
9 1nms ENSP00000311032 NA C2 2 H Caspase-3 tethered to irreversible inhibitor APOPTOSIS, HYDROLASE
9 2g71_1 ENSP00000269582 NA NPS 1 H Structure of hPNMT with inhibitor 3-fluoromethyl-7-trifluoropropyl-THIQ and AdoHcy TRANSFERASE
9 1w9q_2 ENSP00000260130 NA NPS 1 H CRYSTAL STRUCTURE OF THE PDZ TANDEM OF HUMAN SYNTENIN IN COMPLEX WITH TNEFAF PEPTIDE ADHESION/COMPLEX
9 1n45_1 ENSP00000216117 NA NPS 1 H X-RAY CRYSTAL STRUCTURE OF HUMAN HEME OXYGENASE-1 (HO-1) IN COMPLEX WITH ITS SUBSTRATE HEME OXIDOREDUCTASE
9 2hci ENSP00000351671 NA C2 2 H Structure of Human Mip-3a Chemokine IMMUNE SYSTEM
9 1yye ENSP00000343925 NA C2 2 H Crystal structure of estrogen receptor beta complexed with way-202196 TRANSCRIPTION
9 2car ENSP00000369456 NA C2 2 H CRYSTAL STRUCTURE OF HUMAN INOSINE TRIPHOSPHATASE HYDROLASE
9 1xu9 ENSP00000261465 NA D2 4 H Crystal Structure of the Interface Closed Conformation of 11b-hydroxysteroid dehydrogenase isozyme 1 OXIDOREDUCTASE
9 2nsx_2 ENSP00000357357 NA NPS 1 H Structure of acid-beta-glucosidase with pharmacological chaperone provides insight into Gaucher disease Hydrolase
9 2an5_1 ENSP00000269582 NA NPS 1 H Structure of human PNMT complexed with S-adenosyl-homocysteine and an inhibitor, trans-(1S,2S)-2-amino-1-tetralol TRANSFERASE
9 2gmf_1 ENSP00000296871 NA NPS 1 H HUMAN GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR GROWTH FACTOR
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